PUBLIKASJONSLISTE

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Norsk Systemisk bindevevssykdom og vaskulittregister (NOSVAR) har fra og med 2010 bidratt til forskningsdata som er publisert i form av mer enn 60 vitenskapelige internasjonale manuskripter, alle oppført i forskningsdatabasen PuMed (https://www.ncbi.nlm.nih.gov/pubmed ). Data fra NOSVAR er også brukt i 6 norske og en utenlandsk PhD (doktorgrad).


PubMed-listede publikasjoner der NOSVAR-data er brukt 2017-2010

2017

Interdisciplinary, Comprehensive Oral and Ocular Evaluation of Patients with Primary Sjögren’s Syndrome. Tashbayev B, Rusthen S, Young A, Herlofson BB, Hove LH, Singh PB, Rykke M, Aqrawi LA, Chen X, Utheim ØA, Utheim TP, Palm Ø, Jensen JL. Sci Rep. 2017 Sep 7;7(1):10761. doi: 10.1038/s41598-017-10809-w.

Meibomian gland features in a Norwegian cohort of patients with primary Sjögren´s syndrome.Chen X, Utheim ØA, Xiao J, Adil MY, Stojanovic A, Tashbayev B, Jensen JL, Utheim TP. PLoS One. 2017 Sep 8;12(9):e0184284. doi: 10.1371/journal.pone.0184284. eCollection 2017.

Stromelysin-2 (MMP-10), a novel mediator of vascular remodeling underlying pulmonary hypertension associated with systemic sclerosis. Avouac J, Guignabert C, Hoffmann-Vold AM, Ruiz B, Dorfmuller P, Pezet S, Amar O, Tu L, Van Wassenhove J, Sadoine J, Launay D, Elhai M, Cauvet A, Subramaniam A, Resnick R, Hachulla E, Molberg Ø, Kahan A, Humbert M, Allanore Y.Arthritis Rheumatol. 2017 Aug 13. doi: 10.1002/art.40229.

Long-term follow-up in primary Sjögren’s syndrome reveals differences in clinical presentation between female and male patients. Ramírez Sepúlveda JI, Kvarnström M, Eriksson P, Mandl T, Norheim KB, Johnsen SJ, Hammenfors D, Jonsson MV, Skarstein K, Brun JG; DISSECT consortium, Rönnblom L, Forsblad-d’Elia H, Magnusson Bucher S, Baecklund E, Theander E, Omdal R, Jonsson R, Nordmark G, Wahren-Herlenius M.Biol Sex Differ. 2017 Aug 8;8(1):25. doi: 10.1186/s13293-017-0146-6.

Oral disorders, saliva secretion, and oral health-related quality of life in patients with primary Sjögren’s syndrome. Rusthen S, Young A, Herlofson BB, Aqrawi LA, Rykke M, Hove LH, Palm Ø, Jensen JL, Singh PB.Eur J Oral Sci. 2017 Aug;125(4):265-271. doi: 10.1111/eos.12358. Epub 2017 Jun 23.

TNF inhibitors appear to inhibit disease progression and improve outcome in Takayasu arteritis; an observational, population-based time trend study.Gudbrandsson B, Molberg Ø, Palm Ø.Arthritis Res Ther. 2017 May 18;19(1):99. doi: 10.1186/s13075-017-1316-y.

Timing of onset affects arthritis presentation pattern in antisyntethase syndrome.González-Gay MA, Montecucco C, Selva-O’Callaghan A, Trallero-Araguas E, Molberg O, Andersson H, Rojas-Serrano J, Perez-Roman DI, Bauhammer J, Fiehn C, Neri R, Barsotti S, Lorenz HM, Doria A, Ghirardello A, Iannone F, Giannini M, Franceschini F, Cavazzana I, Triantafyllias K, Benucci M, Infantino M, Manfredi M, Conti F, Schwarting A, Sebastiani G, Iuliano A, Emmi G, Silvestri E, Govoni M, Scirè CA, Furini F, Lopez-Longo FJ, Martínez-Barrio J, Sebastiani M, Manfredi A, Bachiller-Corral J, Sifuentes Giraldo WA, Cimmino MA, Cosso C, Belotti Masserini A, Cagnotto G, Codullo V, Romano M, Paolazzi G, Pellerito R, Saketkoo LA, Ortego-Centeno N, Quartuccio L, Batticciotto A, Bartoloni Bocci E, Gerli R, Specker C, Bravi E, Selmi C, Parisi S, Salaffi F, Meloni F, Marchioni E, Pesci A, Dei G, Confalonieri M, Tomietto P, Nuno L, Bonella F, Pipitone N, Mera-Valera A, Perez-Gomez N, Gerzeli S, Lopez-Mejias R, Matos-Costa CJ, Pereira da Silva JA, Cifrian J, Alpini C, Olivieri I, Blázquez Cañamero MÁ, Rodriguez Cambrón AB, Castañeda S, Cavagna L; AENEAS (American and European NEtwork of Antisynthetase Syndrome) collaborative group. Clin Exp Rheumatol. 2017 Jul 26. [Epub ahead of print]

Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts.Volkmann ER, Hoffmann-Vold AM, Chang YL, Jacobs JP, Tillisch K, Mayer EA, Clements PJ, Hov JR, Kummen M, Midtvedt Ø, Lagishetty V, Chang L, Labus JS, Molberg Ø, Braun J.BMJ Open Gastroenterol. 2017 Apr 1;4(1):e000134. doi: 10.1136/bmjgast-2017-000134. eCollection 2017.PMID:28761687

Identification of potential saliva and tear biomarkers in primary Sjögren’s syndrome, utilising the extraction of extracellular vesicles and proteomics analysis.Aqrawi LA, Galtung HK, Vestad B, Øvstebø R, Thiede B, Rusthen S, Young A, Guerreiro EM, Utheim TP, Chen X, Utheim ØA, Palm Ø, Jensen JL. Arthritis Res Ther. 2017 Jan 25;19(1):14. doi: 10.1186/s13075-017-1228-x.

Comparative analyses of muscle MRI and muscular function in anti-synthetase syndrome patients and matched controls: a cross-sectional study.Andersson H, Kirkhus E, Garen T, Walle-Hansen R, Merckoll E, Molberg Ø. Arthritis Res Ther. 2017 Jan 25;19(1):17. doi: 10.1186/s13075-017-1219-y.

Cardiopulmonary Disease Development in Anti-RNA Polymerase III-positive Systemic Sclerosis: Comparative Analyses from an Unselected, Prospective Patient Cohort.Hoffmann-Vold AM, Midtvedt Ø, Tennøe AH, Garen T, Lund MB, Aaløkken TM, Andreassen AK, Elhage F, Brunborg C, Taraldsrud E, Molberg Ø.J Rheumatol. 2017 Jan 15. pii: jrheum.160867. doi: 10.3899/jrheum.160867. [Epub ahead of print]

Immune-array Analysis in Sporadic Inclusion Body Myositis Reveals HLA-DRB1 Amino Acid Heterogeneity across the Myositis Spectrum.Rothwell S, Cooper RG, Lundberg IE, Gregersen PK, Hanna MG, Machado PM, Herbert MK, Pruijn GJ, Lilleker JB, Roberts M, Bowes J, Seldin MF, Vencovsky J, Danko K, Limaye V, Selva-O’Callaghan A, Platt H, Molberg Ø, Benveniste O, Radstake TR, Doria A, De Bleecker J, De Paepe B, Gieger C, Meitinger T, Winkelmann J, Amos CI, Ollier WE, Padyukov L, Lee AT, Lamb JA, Chinoy H. Arthritis Rheumatol. 2017 Jan 13. doi: 10.1002/art.40045

Progression and mortality of interstitial lung disease in mixed connective tissue disease: a long-term observational nationwide cohort study. Reiseter S, Gunnarsson R, Mogens Aaløkken T, Brit Lund M, Mynarek G, Corander J, Haydon J, Molberg Ø. Rheumatology (Oxford). 2017 Mar 29. doi: 10.1093/rheumatology/kex077. [Epub ahead of print] PMID:28379478

Immune-Array Analysis in Sporadic Inclusion Body Myositis Reveals HLA-DRB1 Amino Acid Heterogeneity Across the Myositis Spectrum. Rothwell S, Cooper RG, Lundberg IE, Gregersen PK, Hanna MG, Machado PM, Herbert MK, Pruijn GJM, Lilleker JB, Roberts M, Bowes J, Seldin MF, Vencovsky J, Danko K, Limaye V, Selva-O’Callaghan A, Platt H, Molberg Ø, Benveniste O, Radstake TRDJ, Doria A, De Bleecker J, De Paepe B, Gieger C, Meitinger T, Winkelmann J, Amos CI, Ollier WE, Padyukov L, Lee AT, Lamb JA, Chinoy H; Myositis Genetics Consortium. Arthritis Rheumatol. 2017 May;69(5):1090-1099. doi: 10.1002/art.40045. Epub 2017 Apr 4.PMID:28086002

2016

 AGenome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis. Carmona FD, et al Am J Hum Genet. 2016 Dec 21. pii: S0002-9297(16)30491-8. doi:

Takayasu arteritis and pregnancy; – a population based study on outcome and mother-child related concerns. Gudbrandsson B, Wallenius M, Garen T, Henriksen T, Molberg Ø, Palm Ø. Arthritis Care Res (Hoboken). 2016 Nov 3. doi: 10.1002/acr.23146.

Endostatin is higher and associated with pulmonary involvement in primary Sjögren’s syndrome. Øyvind Palm, Thor Ueland, Torhild Garen, Annika E. Michelsen, Silje Reiseter, Pål Aukrust, Trond Mogens Aaløkken, Øyvind Molberg, Clin Exp Rheumatol, 2016

Prevalence, incidence and disease characteristics of Takayasu Arteritis differ by ethnic background; data from a large, population based cohort resident in Southern Norway. Gudbrandsson B, Molberg Ø, Garen T, Palm Ø. Arthritis Care Res (Hoboken). 2016 May 9. doi: 10.1002/acr.22931.

Antiphospholipid antibodies are associated with low levels of complement C3 and C4 in patients with systemic lupus erythematosus. Garabet L, Gilboe IM, Mowinckel MC, Flem Jacobsen A, Mollnes TE, Sandset PM, Jacobsen EM. Scand J Immunol. 2016 May 2. doi: 10.1111/sji.12445.

Cross-disease Meta-analysis of Genome-wide Association Studies for Systemic Sclerosis and Rheumatoid Arthritis Reveals IRF4 as a New Common Susceptibility Locus. López-Isac E, et al. Arthritis Rheumatol. 2016 Apr 25. doi: 10.1002/art.39730. [Epub ahead of print]

Pulmonary Involvement in the Antisynthetase Syndrome: A Comparative Cross-sectional Study. Andersson H, Aaløkken TM, Günther A, Mynarek GK, Garen T, Lund MB, Molberg Ø. J Rheumatol. 2016 Apr 1. pii: jrheum.151067. [Epub ahead of print]

High level of chemokine CCL18 is associated with pulmonary function deterioration, lung fibrosis progression and reduced survival in Systemic Sclerosis.Hoffmann-Vold AM, Tennøe AH, Garen T, Midtvedt Ø, Abraityte A, Aaløkken TM, Lund MB, Brunborg C, Aukrust P, Ueland T, Molberg Ø. Chest. 2016 Mar 18. pii: S0012-3692(16)41642-9. doi: 10.1016/j.chest.2016.03.004. [Epub ahead of print]

Associations between anti-Ro52 antibodies and lung fibrosis in mixed connective tissue disease. Gunnarsson R, El-Hage F, Aaløkken TM, Reiseter S, Lund MB, Garen T; Norwegian MCTD study group, Molberg Ø. Rheumatology (Oxford). 2016 Jan;55(1):103-8. doi: 10.1093/rheumatology/kev300. Epub 2015 Aug 28

2015

A Large-Scale Genetic Analysis Reveals a Strong Contribution of the HLA Class II Region to Giant Cell Arteritis Susceptibility. Carmona FD et al, Am J Hum Genet. 2015 Mar 25

Long-term experience with rituximab in anti-synthetase syndrome-related interstitial lung disease. Andersson H, Sem M, Lund MB, Aaløkken TM, Günther A, Walle-Hansen R, Garen T, Molberg Ø. Rheumatology (Oxford). 2015 Mar 3. pii: kev004. [Epub ahead of print]

High prevalence of inclusion body myositis in Norway; a population-based clinical epidemiology study. Dobloug GC, Antal EA, Sveberg L, Garen T, Bitter H, Stjärne J, Grøvle L, Gran JT, Molberg Ø. Eur J Neurol. 2015 Apr;22(4):672-e41.

A comparison between nailfold capillaroscopy patterns in adulthood in juvenile and adult-onset systemic sclerosis: A EUSTAR exploratory study. Ingegnoli F et al EUSTAR Group: Microvasc Res. 2015 Aug 4

Survival and cancer risk in an unselected and complete Norwegian idiopathic inflammatory myopathy cohort. Dobloug GC, Garen T, Brunborg C, Gran JT, Molberg Ø. Semin Arthritis Rheum. 2015 Jun 17

Predictive Value of Serial High-Resolution Computed Tomography Analyses and Concurrent Lung Function Tests in Systemic Sclerosis. Hoffmann-Vold AM, Aaløkken TM, Lund MB, Garen T, Midtvedt Ø, Brunborg C, Gran JT, Molberg Ø. Arthritis Rheumatol. 2015 May;67

Prevalence and clinical characteristics of adult polymyositis and dermatomyositis; data from a large and unselected Norwegian cohort. Dobloug C, Garen T, Bitter H, Stjärne J, Stenseth G, Grøvle L, Sem M, Gran JT, Molberg O.Ann Rheum Dis. 2015 Aug;74

The HLA profiles of mixed connective tissue disease differ distinctly from the profiles of clinically related connective tissue diseases. Flåm ST, Gunnarsson R, Garen T; Norwegian MCTD Study Group, Lie BA, Molberg O. Rheumatology (Oxford). 2015 Mar;54

Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database. Maurer B et al, Ann Rheum Dis. 2015 Jun;74

Performance of the 2013 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Systemic Sclerosis (SSc) in Large, Well-defined Cohorts of SSc and Mixed Connective Tissue Disease. Hoffmann-Vold AM, Gunnarsson R, Garen T, Midtvedt O, Molberg O, J Rheumatol. 2015 Jan;42

Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational  Reiseter, S, Molberg, O, Gunnarsson R, Lund MB, Aalokken TM, Aukrust P, Ueland T, Garen T, Brunborg C, Michelsen A, Abraityte A, Hoffmann-Vold AM. Arthritis Res Ther. 2015 Aug 28;17:231. doi: 10.1186/s13075-015-0756-5.

Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. Rothwell S, et al; Myositis Genetics Consortium.Ann Rheum Dis. 2015 Sep 11. pii: annrheumdis-2015-208119. doi: 10.1136/annrheumdis-2015-208119.

Associations between anti-Ro52 antibodies and lung fibrosis in mixed connective tissue disease. Gunnarsson R, El-Hage F, Aaløkken TM, Reiseter S, Lund MB, Garen T; Norwegian MCTD study group, Molberg Ø. Rheumatology (Oxford). 2016 Jan;55(1):103-8. doi: 10.1093/rheumatology/kev300

2014

Influence of the IL17A locus in giant cell arteritis susceptibility. Márquez A, et al. J.Ann Rheum Dis. 2014 Jun 11. pii: annrheumdis-2014-205261. doi: 10.1136/annrheumdis-2014-205261. [Epub ahead of print]

Mortality and years of potential life loss in systemic lupus erythematosus: a population-based cohort study. Lerang K, Gilboe IM, Telle SD, Gran JT; Lupus

Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group. Jordan S et al; Ann.Rheum Dis.

Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR  prosepctive study. Avouac J et al. Ann Rheum Dis

A gender gap in primary and secondary heart dysfunction in systemic sclerosis: a EUSTAR prospective study. Elhai M et al. Ann Rheum Dis.

Livskvalitet, munntørrhet og kliniske funn hos pasienter med Sjögrens syndrom. Melina Grigoriou, Tone Berge Enger, Helle Charlotte Øveraasen, Øyvind Palm, Torhild Garen og Janicke Liaaen Jensen. Nor  Tannelgeforen  Tid. 2014

A candidate gene approach identifies an IL33 genetic variant as a novel genetic risk factor for GCA. Márquez A, et al. PLoS One. 2014 Nov 19;9(11):e113476.

2013

Pulmonary Involvement in Sjøgrens syndrom, Palm Ø, Garen T, Gran JT et al  Rheumatology 2013

Pulmonary Hypertension in MCTD, Gunnarsson R, et al. Rheumatology 2013

Survival and causes of death in an unselected and complete cohort of Norwegian patients with systemic sclerosis. Hoffmann-Vold AM, Molberg Ø, Midtvedt Ø, Garen T, Gran JT. J Rheumatol. 2013 Jul;40(7):1127-33. doi: 10.3899/jrheum.121390. Epub 2013 May 1.

Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility.Diaz-Gallo LM, et al. Ann Rheum Dis. 2013 Jul;72(7):1233-8. doi: 10.1136/annrheumdis-2012-202357. Epub 2012 Nov 21

Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis.Serrano A, Márquez A, et al, Ann Rheum Dis. 2013 Aug 14. doi: 10.1136/annrheumdis-2013-203641.

Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study.Bossini-Castillo L, et al AM Hoffmann-Vold medforfatter,Ann Rheum Dis 2013;72:602-607 doi:10.1136/annrheumdis-2012-201888

2012

Prevalence and severity of interstitial lung disease in mixed connective tissue disease: a nationwide, cross-sectional study. Gunnarsson R, et al.  Ann Rheum Dis. 2012 Dec;71(12):1966-72. doi: 10.1136/annrheumdis-2011-201253

A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis. Bossini-Castillo L, AM Hoffmann-Vold medforfatter. Rheumatology (Oxford). 2011 Nov;50(11):1976-81.

Prevalence of systemic sclerosis in south-east Norway. Hoffmann-Vold AM, et al T Garen medforfatter. Rheumatology (Oxford). 2012 Sep;51(9):1600-5.

Differences between rheumatologists and other internists regarding diagnosis and treatment of systemic lupus erythematosus. Lerang K, Gilboe IM, Gran JT. Rheumatology (Oxford). 2012 Apr;51(4):663-9

High incidence and prevalence of systemic lupus erythematosus in Norway. Lerang K, Gilboe I, Garen T, Thelle D, Gran J. Lupus. 2012;21(12):1362-9

Influence of the IL6 Gene in Susceptibility to Systemic Sclerosis. Cénit MC, et al,  J Rheumatol. 2012 Oct 1

2011

Oral distress in primary Sjögren’s syndrome: implications for health-related quality of life. Enger TB et al

Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis.; Carmona FD,  Ann Rheum Dis. 2011 Nov

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. Gorlova O. . PLoS Genet. 2011 Jul; 7(7)

The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis. Martin JE et al. Genes Immun. 2011 Oct 20.

Confirmation of association of the macrophage migration inhibitory factor gene with systemic sclerosis in a large European population. Bossini-Castillo L et al. Rheumatology (Oxford). 2011 Nov.

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations. Bossini-Castillo L et al. Hum Mol Genet. 2011 Nov 29.

The prevalence and incidence of mixed connective tissue disease: a national multicentre survey of Norwegian patients. Gunnarsson R, et al PAHNOR1 Study Group. Ann Rheum Dis. 2011 Jun;70(6):1047-51.

2010

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort.; Bossini-Castillo L et al. Ann Rheum Dis. 2010 Dec 27.

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Radstake TR et al.  Nat Genet. 2010 May; 42(5):426-9. Epub 2010 Apr 11.